This is Sindhu's third consecutive first round loss.
Sindhu's disappointing performances have seen her to slip to 17th in the BWF world rankings, her worst slump in a decade. Her previous highest ranking was 2nd in 2016.
Two-time Olympic medallist PV Sindhu faltered in the deciding game to lose to World No. 8 Pornpawee Chochuwong of Thailand in the women's singles second round of the Indonesia Open Super 1000 badminton tournament in Jakarta on Thursday.
India will host the World Championships for the first time since 2009, with the event seen as a key test of the country's ability to deliver large-scale international tournaments as it eyes the 2036 Olympics.
After a string of disappointing results, PV Sindhu parted ways with coach Park Tae Sang
HS Prannoy battled his way into the semifinal of the men's singles with a thrilling three-game win over Malaysia Lee Zii Jia to assure India a badminton medal
Congratulatory messages pour in for badminton superstar PV Sindhu on winning her second Olympic medal on Sunday.
India's leading badminton player Saina Nehwal has dropped four places to be No 9 in the latest world rankings while P V Sindhu remains No 10 despite winning a silver medal in the Rio Olympics.
P V Sindhu and H S Prannoy sailed into the quarter-finals of the women's and men's singles badminton event with easy victories at the Asian Games.
Tanvi, Unnati and Bhargav Ram-Viswa Tej to lead strong Indian line-up in BWF World Junior Championships
With her silver from Rio, PV Sindhu is already India's most successful female Olympian but her World Championship triumph also boosted the nation's hopes of a medal in Tokyo next year.
This is also India's third Olympics medal in badminton - Saina Nehwal had won the bronze at the 2012 London Olympics.
Tunjung dominated early using her delectable drops to good use and race to an 11-4 lead at the break. With Sindhu struggling with her strokes, it was all over too soon.
'In women's singles now, there are a lot of long rallies and long matches, being consistent. I am confident in that now.'
Indian shuttlers handed tough draws, Lakshya Sen to face world No 1 Shi Yu Qi in opener
PV Sindhu recorded a consolation win over China's He Bingjiao in the third Group A match to end her campaign on a positive note
Sindhu beat the Thai 21-23, 21-13, 21-18 after a tough contest.
I will continue, albeit after a small break: PV Sindhu
The Indian ace has previously won a silver medal in the 2016 Rio Games and a bronze in the Tokyo edition.
Sindhu, Lakshya win openers; Sai Praneeth loses in US Open
'In general, I needed a short break from sports because I had worked extremely hard for the Paralympics. I was happy with my performance, but not winning a medal left me a little disappointed. I channelled my energy into other things... overall, the past year has been wonderful in its own way.'
India's first world badminton champion P V Sindhu said her next aim is to bag the gold medal at the Tokyo Olympics in 2020.
A third straight Olympics medal eluded P V Sindhu after a shock exit from the Paris Games following a straight-games defeat to China's world No. 6 He Bingjiao in the women's singles badminton pre-quarter-finals in Paris on Thursday.
Two-time Olympic medallist PV Sindhu and HS Prannoy have been handed relatively easy groups for the Paris Games, which begin on July 26.
Sindhu won 12-21, 23-21, 21-19 in the women's singles quarter-finals match that lasted 71 minutes.
Given the Indian duo's struggles with fitness and injury over the last few weeks, this was a commendable win.
It's high time we took fashion lessons from her.
B Sumeeth Reddy and Ashwini Ponnappa, however, suffered a 21-23, 21-13, 12-21 loss against Korean pair of Song hyun Cho and Lee Jung Hyun in their mixed doubles opening round.
Sindhu will be looking to do one better than her last outing at the Olympics where she won the badminton silver at the Rio Games in 2016.
Sindhu celebrated her 26th birthday and her nephew Aaryan's 3rd birthday.
PV Sindhu stormed into the pre-quarterfinals of the Olympic Games' women's singles competition
In other India-related results, it was curtains for Ashmita Chaliha, who lost 17-21, 16-21 to Indonesia's world no. 7 Gregoria Mariska Tunjung in 35 minutes. Both teams had received a bye in their opening match.
A former world champion, Sindhu is one of the favourites to win the women's singles gold medal in Birmingham, having won the silver and bronze in the last two editions at Gold Coast and Glasgow.
Two-time Olympic-medallist P V Sindhu made a winning return from a lengthy injury lay-off as India stunned formidable China 3-2 in the women's competition of the Badminton Asia Team Championships in Shah Alam, Malaysia on Wednesday.
Also seen interacting with Prime Minister Modi was Olympic gold medallist javelin thrower Neeraj Chopra over a bowl of choorma.
Chief coach of the Indian badminton team, Pullela Gopichand also congratulated the Tokyo Olympics badminton bronze medal winner.
Winning an elusive Olympic gold in Tokyo next year is PV Sindhu's top priority but reigning world champion's immediate target is to do well in the coming tournaments as this is the qualifying year for the quadrennial extravaganza.
IOA also announced that Sindhu, India's only woman athlete to win back-to-back Olympic medals, will be the flag bearer of the Indian contingent during the opening ceremony on July 26, alongside ace table tennis player Achanta Sharath Kamal.
PV Sindhu on Sunday said she is "definitely" going to play for the next couple of years even as the 2028 Los Angeles Games remains at the back of her mind.
Double Olympic medallist PV Sindhu, who is returning from an ankle injury, begins her campaign against former World Champion Carolina Marin of Spain in the first round of Malaysia Open.